National Breast Cancer Awareness Month. Question. How does CBD help with breast cancer?
As the son of a breast cancer survivor, I can tell you first hand that the journey to battle this horrible disease is challenging to say the least. Its unforgiving and takes away the right to choose for your loved one and all of those who help support. With that said, a good team of physicians, specialists, family and friends goes along way. Blessed to have you all on our side.
In this journey, you often ask questions that some may not have an answer for like...
1. What are the treatment options?
2. Who is the best in this area of cancer treatments?
3. Are there alternative medicines we should consider?
4. What other resources are out there to help support our needs?
From the world of CBD and its holistic approach we often get questions regarding CBD and its effectiveness battling this disease. Of course we can not promise to treat, cure or mitigate disease. Additionally, its always a good idea to discuss the use of CBD with your primary physician or contact a local holistic doctor for questions/answers.
We can say that many studies have found that CBD significantly reduced breast cancer cell proliferation and invasion. These are just a few studies addressing the potential of cannabinoids to help treat cancer. It has been know to help by interacting with endocannabinoid system (https://www.healthline.com/health/endocannabinoid-system), which means it can help reduce side effects of breast cancer treatment like pain, anxiety, insomnia, nausea, and vomiting.
From the National Library of Medicine. https://pubmed.ncbi.nlm.nih.gov/30987191/
Cannabinoids (CBs) from Cannabis sativa provide relief for tumor-associated symptoms (including nausea, anorexia, and neuropathic pain) in the palliative treatment of cancer patients. Additionally, they may decelerate tumor progression in breast cancer patients. Indeed, the psychoactive delta-9-tetrahydrocannabinol (THC), non-psychoactive cannabidiol (CBD) and other CBs inhibited disease progression in breast cancer models. The effects of CBs on signaling pathways in cancer cells are conferred via G-protein coupled CB-receptors (CB-Rs), CB1-R and CB2-R, but also via other receptors, and in a receptor-independent way. THC is a partial agonist for CB1-R and CB2-R; CBD is an inverse agonist for both. In breast cancer, CB1-R expression is moderate, but CB2-R expression is high, which is related to tumor aggressiveness. CBs block cell cycle progression and cell growth and induce cancer cell apoptosis by inhibiting constitutive active pro-oncogenic signaling pathways, such as the extracellular-signal-regulated kinase pathway. They reduce angiogenesis and tumor metastasis in animal breast cancer models. CBs are not only active against estrogen receptor-positive, but also against estrogen-resistant breast cancer cells. In human epidermal growth factor receptor 2-positive and triple-negative breast cancer cells, blocking protein kinase B- and cyclooxygenase-2 signaling via CB2-R prevents tumor progression and metastasis. Furthermore, selective estrogen receptor modulators (SERMs), including tamoxifen, bind to CB-Rs; this process may contribute to the growth inhibitory effect of SERMs in cancer cells lacking the estrogen receptor. In summary, CBs are already administered to breast cancer patients at advanced stages of the disease, but they might also be effective at earlier stages to decelerate tumor progression.
There is still a lot of research and clinic studies needed, but the experts are starting getting more positive information. We always recommend researching and talking to a doctor who has studied CBD before using. CBD may be healthy alternative for your loved ones. For more information about CBD and how it works with your ECS system, please call or schedule online for a private consultation.
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